The histone deacetylase inhibitor panobinostat as a radiosensitiser in bladder cancer

The histone deacetylase inhibitor panobinostat as a radiosensitiser in bladder cancer

<p>Muscle invasive bladder cancer (MIBC) has a poor prognosis. Currently, therapy consists of radical radiotherapy or cystectomy with or without chemotherapy. The average age of patients with MIBC is high and older patients are less able to tolerate surgery or chemoradiation due to their impai...

Полное описание

Библиографические подробности
Главный автор:	Groselj, B
Другие авторы:	Kiltie, A
Формат:	Диссертация
Язык:	English
Опубликовано:	2014
Предметы:	Oncology Biology

Схожие документы

Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression
по: Groselj, B, и др.
Опубликовано: (2013)

Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
по: Groselj, B, и др.
Опубликовано: (2013)

Histone deacetylase inhibitors as radiosensitisers: Effects on DNA damage signalling and repair
по: Groselj, B, и др.
Опубликовано: (2013)

Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair.
по: Groselj, B, и др.
Опубликовано: (2013)

Histone Deacetylases and Their Potential as Targets to Enhance Tumour Radiosensitisation
по: Jennifer Antrobus, и др.
Опубликовано: (2022-03-01)

The histone deacetylase inhibitor romidepsin spares normal tissues while acting as an effective radiosensitiser in bladder tumours in vivo
по: Paillas, S, и др.
Опубликовано: (2020)

Radiosensitisation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity
по: Groselj, B, и др.
Опубликовано: (2017)

Identification of novel strategies to radiosensitise tumour cells
по: Anbalagan, S
Опубликовано: (2014)

Internalising radioimmunoconjugates to target KRas cancer cells for simultaneous radio-ligand therapy and radiosensitisation
по: Lourenço, J
Опубликовано: (2024)

The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression
по: Lin Xiao, и др.
Опубликовано: (2022-05-01)

The emerging role of histone deacetylase (HDAC) inhibitors in urological cancers.
по: Sharma, N, и др.
Опубликовано: (2013)

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma
по: Monica Phimmachanh, и др.
Опубликовано: (2020-10-01)

The HDAC Inhibitor Panobinostat Promotes Expression of Delta 133p53 Variants in TP53 Wild-type Bladder Cancer Cells
по: Groselj, B, и др.
Опубликовано: (2012)

Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma
по: AGM Mostofa, и др.
Опубликовано: (2021-12-01)

Histone Deacetylases and Histone Deacetylase Inhibitors: Molecular Mechanisms of Action in Various Cancers
по: Masumeh Sanaei, и др.
Опубликовано: (2019-01-01)

Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis.
по: Martina Korfei, и др.
Опубликовано: (2018-01-01)

Acetylation and Histone Deacetylase Inhibitors in Cancer
по: Madeleine S. Q. Kortenhorst, и др.
Опубликовано: (2006-01-01)

The Pan-Deacetylase Inhibitor Panobinostat Inhibits Growth of Hepatocellular Carcinoma Models by Alternative Pathways of Apoptosis
по: Pietro Di Fazio, и др.
Опубликовано: (2010-01-01)

Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines.
по: Yukiko Hazama, и др.
Опубликовано: (2022-01-01)

HBI-8000, HUYABIO Lead Clinical Program, Is a Selective Histone Deacetylase Inhibitor With Therapeutic Benefits in Leukemia and in Solid Tumors
по: Farbod Shojaei, и др.
Опубликовано: (2022-01-01)

SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A
по: Ruicai Gu, и др.
Опубликовано: (2023-10-01)

Inhibition of DNA methyltransferase activity and expression by treatment with the pan-deacetylase inhibitor panobinostat in hepatocellular carcinoma cell lines
по: Zopf Steffen, и др.
Опубликовано: (2012-09-01)

Potential of histone deacetylase inhibitors for the therapy of ovarian cancer
по: Fengyi Guo, и др.
Опубликовано: (2022-11-01)

Nanotechnology-Based Histone Deacetylase Inhibitors for Cancer Therapy
по: Bin Tu, и др.
Опубликовано: (2020-06-01)

Tetrahydroisoquinolines as novel histone deacetylase inhibitors for treatment of cancer
по: Danqi Chen, и др.
Опубликовано: (2016-01-01)

Characterisation of the histone acetyltransferase KAT7 as a novel target for radiosensitisation
по: Bittner, M
Опубликовано: (2017)

The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo
по: Liebes Leonard, и др.
Опубликовано: (2007-10-01)

Histone deacetylase inhibitors in multiple myeloma
по: Sarah Deleu, и др.
Опубликовано: (2009-06-01)

The application of histone deacetylases inhibitors in glioblastoma
по: Rui Chen, и др.
Опубликовано: (2020-07-01)

Antidepressant Actions of Histone Deacetylase Inhibitors
по: Haggarty, Stephen J., и др.
Опубликовано: (2010)

Epigenetic drug screening defines a PRMT5 inhibitor–sensitive pancreatic cancer subtype
по: Felix Orben, и др.
Опубликовано: (2022-05-01)

Dietary fibre manipulation as a potential endogenous mechanism of radiosensitisation in bladder cancer
по: Then, CK
Опубликовано: (2022)

Photocaged Histone Deacetylase Inhibitors as Prodrugs in Targeted Cancer Therapy
по: Fabian B. Kraft, и др.
Опубликовано: (2023-02-01)

p66ShcA potentiates the cytotoxic response of triple-negative breast cancers to PARP inhibitors
по: Eduardo Cepeda Cañedo, и др.
Опубликовано: (2021-02-01)

Histone Deacetylase Inhibitor Panobinostat Benefits the Therapeutic Efficacy of Oncolytic Herpes Simplex Virus Combined with PD-1/PD-L1 Blocking in Glioma and Squamous Cell Carcinoma Models
по: Yinglin Wu, и др.
Опубликовано: (2022-12-01)

A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60
по: Rahul Kumar, и др.
Опубликовано: (2022-07-01)

Translational development of MyD88 as a biomarker for selecting patients with lymphoma responsive to histone deacetylase inhibitors
по: Sheikh, S
Опубликовано: (2017)

Role of Histone Deacetylase 6 and Histone Deacetylase 6 Inhibition in Colorectal Cancer
по: Ana Vuletić, и др.
Опубликовано: (2023-12-01)

Role of histone deacetylases and their inhibitors in neurological diseases
по: Li-Ying Zhang, и др.
Опубликовано: (2024-10-01)

Histone Deacetylase Inhibitors from Marine Invertebrates
по: Claudio Luparello, и др.
Опубликовано: (2020-11-01)