Molecular mechanism of lipopeptide presentation by CD1a.

CD1a is expressed on Langerhans cells (LCs) and dendritic cells (DCs), where it mediates T cell recognition of glycolipid and lipopeptide antigens that contain either one or two alkyl chains. We demonstrate here that CD1a-restricted T cells can discriminate the peptide component of didehydroxymycoba...

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Bibliographic Details
Main Authors: Zajonc, D, Crispin, MD, Bowden, T, Young, D, Cheng, T, Hu, J, Costello, C, Rudd, P, Dwek, R, Miller, M, Brenner, M, Moody, D, Wilson, I
Format: Journal article
Language:English
Published: 2005