Translating the promise of 5HT4 receptor agonists for the treatment of depression

Animal experimental studies suggest that 5-HT4 receptor activation holds promise as a novel target for the treatment of depression and cognitive impairment. 5-HT4 receptors are post-synaptic receptors that are located in striatal and limbic areas known to be involved in cognition and mood. Consisten...

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Bibliographic Details
Main Authors: Murphy, SE, de Cates, AN, Gillespie, AL, Godlewska, BR, Scaife, JC, Wright, LC, Cowen, PJ, Harmer, CJ
Format: Journal article
Language:English
Published: Cambridge University Press 2020