HLA-DM stabilizes the empty MHCII binding groove: a model using customized Natural Move Monte Carlo

MHC class II molecules bind peptides derived from extracellular proteins that have been ingested by antigen-presenting cells and display them to the immune system. Peptide loading occurs within the antigen-presenting cell and is facilitated by HLA-DM. HLA-DM stabilises the open conformation of the M...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Demharter, S, Knapp, B, Deane, C, Minary, P
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: American Chemical Society 2019