HLA-DM stabilizes the empty MHCII binding groove: a model using customized Natural Move Monte Carlo

MHC class II molecules bind peptides derived from extracellular proteins that have been ingested by antigen-presenting cells and display them to the immune system. Peptide loading occurs within the antigen-presenting cell and is facilitated by HLA-DM. HLA-DM stabilises the open conformation of the M...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Demharter, S, Knapp, B, Deane, C, Minary, P
स्वरूप: Journal article
भाषा:English
प्रकाशित: American Chemical Society 2019