Vitamin K epoxide reductase: homology, active site and catalytic mechanism.

Vitamin K epoxide reductase (VKOR) recycles reduced vitamin K, which is used subsequently as a co-factor in the gamma-carboxylation of glutamic acid residues in blood coagulation enzymes. VKORC1, a subunit of the VKOR complex, has recently been shown to possess this activity. Here, we show that VKOR...

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Bibliographic Details
Main Authors: Goodstadt, L, Ponting, C
Format: Journal article
Language:English
Published: 2004