Electron-microscopy of intact nuclear DNA from human cells.
Structures retaining many of the morphological features of nuclei may be released by lysing human cells in a non-ionic detergent and 2 M NaCl. Such nucleoids contain all the nuclear DNA packaged within a flexible cage of RNA and protein. HeLa nucleoids have been spread at an air-water interface and...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
1979
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