Electron-microscopy of intact nuclear DNA from human cells.

Structures retaining many of the morphological features of nuclei may be released by lysing human cells in a non-ionic detergent and 2 M NaCl. Such nucleoids contain all the nuclear DNA packaged within a flexible cage of RNA and protein. HeLa nucleoids have been spread at an air-water interface and...

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Bibliographic Details
Main Authors: McCready, S, Akrigg, A, Cook, P
Format: Journal article
Language:English
Published: 1979