Algebraic systems biology: a case study for the Wnt pathway

Steady-state analysis of dynamical systems for biological networks gives rise to algebraic varieties in high-dimensional spaces whose study is of interest in their own right. We demonstrate this for the shuttle model of the Wnt signaling pathway. Here, the variety is described by a polynomial system...

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Bibliographic Details
Main Authors: Gross, E, Harrington, H, Rosen, Z, Sturmfels, B
Format: Journal article
Language:English
Published: Springer US 2015