Identification of neutralising pembrolizumab anti-drug antibodies in patients with melanoma

Development of anti-drug antibodies (ADAs) can interfere with therapeutic monoclonal antibodies and may lead to drug neutralisation and clinical disease progression. Measurement of circulating drug levels and development of ADAs in the setting of anti-programmed cell death-1 agent pembrolizumab has...

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Detalhes bibliográficos
Main Authors: Sasson, SC, Wilkins, LE, Watson, RA, Jolly, C, Brain, O, Klenerman, P, Olsson-Brown, A, Fairfax, BP
Formato: Journal article
Idioma:English
Publicado em: Springer Nature 2021