RNA in defense: CRISPRs protect prokaryotes against mobile genetic elements.
The CRISPR/Cas system in prokaryotes provides resistance against invading viruses and plasmids. Three distinct stages in the mechanism can be recognized. Initially, fragments of invader DNA are integrated as new spacers into the repetitive CRISPR locus. Subsequently, the CRISPR is transcribed and th...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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