Ideafix: a decision tree-based method for the refinement of variants in FFPE DNA sequencing data

Increasingly, treatment decisions for cancer patients are being made from next-generation sequencing results generated from formalin-fixed and paraffin-embedded (FFPE) biopsies. However, this material is prone to sequence artefacts that cannot be easily identified. In order to address this issue, we...

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Bibliographic Details
Main Authors: Tellaetxe-Abete, M, Calvo, B, Lawrie, C
Format: Journal article
Language:English
Published: Oxford University Press 2021