Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8
Regulation of intestinal T-cell responses is crucial for immune homeostasis and prevention of inflammatory bowel disease (IBD). A vital cytokine in regulating intestinal T cells is transforming growth factor-β (TGFβ), which is secreted by cells as a latent complex that requires activation to functio...
Hauptverfasser: | Fenton, T, Kelly, A, Shuttleworth, E, Smedley, C, Atakilit, A, Powrie, F, Campbell, S, Nishimura, S, Sheppard, D, Levison, S, Worthington, J, Lehtinen, M, Travis, M |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
Springer Nature
2016
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