Immunization of mice with a recombinant adenovirus vaccine inhibits the early growth of Mycobacterium tuberculosis after infection.

BACKGROUND: In pulmonary Mycobacterium tuberculosis (Mtb) infection, immune responses are delayed compared to other respiratory infections, so that antigen-specific cells are not detected in the lungs earlier than day 14. Even after parenteral immunization with Bacille Calmette Guerin (BCG) or a sub...

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Détails bibliographiques
Auteurs principaux: Ronan, E, Lee, L, Beverley, P, Tchilian, E
Format: Journal article
Langue:English
Publié: 2009