A mathematical model of dynamic glioma-host interactions: receptor-mediated invasion and local proteolysis.
We present a mathematical model of glioma spread based on cellular movement by receptor-mediated haptotaxis, local proteolysis of healthy tissue components by glioma-derived proteinases, malignant proliferative enhancement and host up-regulation of specific key extracellular matrix (ECM) components...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2005
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