Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane
<p>Small-ring cage hydrocarbons are popular bioisosteres (molecular replacements) for commonly-found <em>para</em>-substituted benzene rings in drug design<sup>1</sup>. The utility of these cage structures derives from their superior pharmacokinetic properties...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Springer Nature
2022
|