Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.

Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.

OBJECTIVES: Ghrelin is a brain-gut peptide with GH-releasing and appetite-inducing activities and a widespread tissue distribution. Ghrelin is the endogenous ligand of the GH secretagogue receptor type 1a (GHS-R1a), and both ghrelin and the GHS-R1a are expressed in the pituitary. There are conflict...

Detaylı Bibliyografya
Asıl Yazarlar:	Nanzer, A, Khalaf, S, Mozid, A, Fowkes, R, Patel, M, Burrin, J, Grossman, AB, Korbonits, M
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2004

Benzer Materyaller

Presence of ghrelin in normal and adenomatous human pituitary.
Yazar:: Korbonits, M, ve diğerleri
Baskı/Yayın Bilgisi: (2001)

Sequence analysis of the PRKAR1A gene in sporadic somatotroph and other pituitary tumours.
Yazar:: Kaltsas, G, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Role of regulatory factors in pituitary tumour formation.
Yazar:: Korbonits, M, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Sequence analysis of the catalytic subunit of PKA in somatotroph adenomas.
Yazar:: Larkin, S, ve diğerleri
Baskı/Yayın Bilgisi: (2014)

Ghrelin: update on a novel hormonal system.
Yazar:: Korbonits, M, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Novel molecular aspects of pituitary adenomas.
Yazar:: Hubina, E, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway.
Yazar:: Chahal, H, ve diğerleri
Baskı/Yayın Bilgisi: (2012)

Enhanced protein kinase B/Akt signalling in pituitary tumours.
Yazar:: Musat, M, ve diğerleri
Baskı/Yayın Bilgisi: (2005)

PPAR-gamma expression in pituitary tumours and the functional activity of the glitazones: evidence that any anti-proliferative effect of the glitazones is independent of the PPAR-gamma receptor.
Yazar:: Emery, M, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

Ghrelin--a hormone with multiple functions.
Yazar:: Korbonits, M, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin.
Yazar:: Mozid, A, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours.
Yazar:: Hubina, E, ve diğerleri
Baskı/Yayın Bilgisi: (2006)

The expression of the growth hormone secretagogue receptor ligand ghrelin in normal and abnormal human pituitary and other neuroendocrine tumors.
Yazar:: Korbonits, M, ve diğerleri
Baskı/Yayın Bilgisi: (2001)

Pathologic Characteristics of Somatotroph Pituitary Tumors—An Observational Single-Center Study
Yazar:: Agnieszka Tomasik, ve diğerleri
Baskı/Yayın Bilgisi: (2023-12-01)

Case Report: Cytologic Description of Somatotroph Pituitary Adenoma in a Cat
Yazar:: Flavio H. Alonso, ve diğerleri
Baskı/Yayın Bilgisi: (2022-07-01)

Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
Yazar:: Azusa Yamato, ve diğerleri
Baskı/Yayın Bilgisi: (2022-11-01)

Akting and cycling: a tale of the pituitary.
Yazar:: Grossman, AB, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Leptin in pituitary adenomas--a novel paracrine regulatory system.
Yazar:: Korbonits, M, ve diğerleri
Baskı/Yayın Bilgisi: (2001)

Silencing of HEPN1 is Responsible for the Aggressive Biological Behavior of Pituitary Somatotroph Adenomas
Yazar:: Hu Peng, ve diğerleri
Baskı/Yayın Bilgisi: (2013-03-01)

Ghrelin and cannabinoids require the ghrelin receptor to affect cellular energy metabolism.
Yazar:: Lim, C, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Ghrelin and cannabinoids require the ghrelin receptor to affect cellular energy metabolism
Yazar:: Lim, C, ve diğerleri
Baskı/Yayın Bilgisi: (2013)

Transsphenoidal hypophysectomy for the treatment of hypersomatotropism secondary to a pituitary somatotroph adenoma in a dog
Yazar:: Matthew M. E. Steele, ve diğerleri
Baskı/Yayın Bilgisi: (2024-01-01)

Somatostatin Analogue Treatment Increases AIP Protein Expression in Somatotroph Tumours from Patients with Acromegaly and in GH3 Cells in vitro.
Yazar:: Chahal, H, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Mutational analysis of ghrelin and the growth hormone secretagogue receptor
Yazar:: Gueorguiev, M, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

Expression of Prolactin Receptor mRNA in Lactotrophs and Somatotrophs of the Chicken Anterior Pituitary Gland
Yazar:: Hiromi Kaneda, ve diğerleri
Baskı/Yayın Bilgisi: (2018-04-01)

Silent Corticotroph and Somatotroph Double Pituitary Adenoma: A Case Report and Review of Literature
Yazar:: Isabella L. Pecorari, ve diğerleri
Baskı/Yayın Bilgisi: (2022-04-01)

Role of ghrelin in the pancreatic exocrine secretion via mitogen-activated protein kinase signaling in rats
Yazar:: Kyung-Hoon Lee, ve diğerleri
Baskı/Yayın Bilgisi: (2017-07-01)

Somatotrophs and lactotrophs: an immunohistochemical study of Gallus domesticus pituitary gland at different stages of induced moult
Yazar:: M. A. Sandhu, ve diğerleri
Baskı/Yayın Bilgisi: (2010-05-01)

The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes.
Yazar:: Garcia, E, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Ghrelin's role as a major regulator of appetite and its other functions in neuroendocrinology.
Yazar:: Lim, C, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro.
Yazar:: Orkin, R, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Comprehensive mapping of somatotroph pituitary neuroendocrine tumour heterogeneity using spatial and single‐cell transcriptomics
Yazar:: Jialin Wang, ve diğerleri
Baskı/Yayın Bilgisi: (2024-11-01)

High level of aneuploidy and recurrent loss of chromosome 11 as relevant features of somatotroph pituitary tumors
Yazar:: Julia Rymuza, ve diğerleri
Baskı/Yayın Bilgisi: (2024-11-01)

The effect of endoscopic transsphenoidal somatotroph tumors resection on pituitary hormones: systematic review and meta-analysis
Yazar:: Ding Nie, ve diğerleri
Baskı/Yayın Bilgisi: (2023-03-01)

Clinical, hormonal and pathomorphological markers of somatotroph pituitary neuroendocrine tumors predicting the treatment outcome in acromegaly
Yazar:: Agnieszka Tomasik, ve diğerleri
Baskı/Yayın Bilgisi: (2022-09-01)

Temozolomide and Capecitabine Treatment for an Aggressive Somatotroph Pituitary Tumor: A Case Report and Literature Review
Yazar:: Atsushi Ishida, ve diğerleri
Baskı/Yayın Bilgisi: (2022-05-01)

Different degrees of somatotroph ablation compromise pituitary growth hormone cell network structure and other pituitary endocrine cell types.
Yazar:: Waite, E, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Ultrastructure and function studies in CD38 null mice reveal a role for CD38 in anterior pituitary somatotrophs
Yazar:: Patel, S, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Cyclins and their related proteins in pituitary tumourigenesis.
Yazar:: Muşat, M, ve diğerleri
Baskı/Yayın Bilgisi: (2010)

Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.
Yazar:: Gueorguiev, M, ve diğerleri
Baskı/Yayın Bilgisi: (2009)