Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

The 6q25.1 locus was first identified via a genome-wide association study (GWAS) in Chinese women and marked by single nucleotide polymorphism (SNP) rs2046210, approximately 180 Kb upstream of ESR1. There have been conflicting reports about the association of this locus with breast cancer in Europea...

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Main Authors: Hein, R, Maranian, M, Hopper, J, Kapuscinski, M, Southey, M, Park, D, Schmidt, M, Broeks, A, Hogervorst, F, Bueno-De-Mesquita, H, Bueno-De-Mesquit, H, Muir, K, Lophatananon, A, Rattanamongkongul, S, Puttawibul, P, Fasching, P, Hein, A, Ekici, AB, Beckmann, M, Fletcher, O, Johnson, N, Dos Santos Silva, I, Peto, J, Sawyer, E, Tomlinson, I, Kerin, M, Miller, N, Marmee, F, Schneeweiss, A, Sohn, C, Burwinkel, B, Guénel, P, Cordina-Duverger, E, Menegaux, F, Truong, T, Bojesen, SE, Nordestgaard, BG, Flyger, H, Milne, R, Perez, J, Zamora, M, Benítez, J, Anton-Culver, H, Ziogas, A, Bernstein, L, Clarke, C, Brenner, H, Müller, H, Arndt, V, Stegmaier, C, Rahman, N, Seal, S, Turnbull, C, Renwick, A, Meindl, A, Schott, S, Bartram, C, Schmutzler, R, Brauch, H, Hamann, U, Ko, Y, Wang-Gohrke, S, Dörk, T, Schürmann, P, Karstens, J, Hillemanns, P, Nevanlinna, H, Heikkinen, T, Aittomäki, K, Blomqvist, C, Bogdanova, N, Zalutsky, I, Antonenkova, N, Bermisheva, M, Prokovieva, D, Farahtdinova, A, Khusnutdinova, E, Lindblom, A, Margolin, S, Mannermaa, A, Kataja, V, Kosma, V, Hartikainen, J, Chen, X, Beesley, J, Lambrechts, D, Zhao, H, Neven, P, Wildiers, H, Nickels, S, Flesch-Janys, D, Radice, P, Peterlongo, P, Manoukian, S, Barile, M, Couch, F, Olson, J, Wang, X, Fredericksen, Z, Giles, G, Baglietto, L, McLean, C, Severi, G, Offit, K, Robson, M, Gaudet, M, Vijai, J, Alnæs, G, Kristensen, V, Børresen-Dale, A, John, E, Miron, A, Winqvist, R, Pylkäs, K, Jukkola-Vuorinen, A, Grip, M, Andrulis, I, Knight, J, Glendon, G, Mulligan, A, Figueroa, J, García-Closas, M, Lissowska, J, Sherman, M, Hooning, M, Martens, J, Seynaeve, C, Collée, M, Hall, P, Humpreys, K, Czene, K, Liu, J, Cox, A, Brock, I, Cross, S, Reed, M, Ahmed, S, Ghoussaini, M, Pharoah, P, Kang, D, Yoo, K, Noh, D, Jakubowska, A, Jaworska, K, Durda, K, Złowocka, E, Sangrajrang, S, Gaborieau, V, Brennan, P, McKay, J, Shen, C, Yu, J, Hsu, H, Hou, M, Orr, N, Schoemaker, M, Ashworth, A, Swerdlow, A, Trentham-Dietz, A, Newcomb, P, Titus, L, Egan, K, Chenevix-Trench, G, Antoniou, A, Humphreys, M, Morrison, J, Chang-Claude, J, Easton, D, Dunning, A
Format: Journal article
Language:English
Published: Public Library of Science 2012