Telomere length shortening in chronic myelogenous leukemia is associated with reduced time to accelerated phase.

Telomere shortening is associated with disease evolution in chronic myelogenous leukemia (CML). We have examined the relationship between diagnostic telomere length and outcome in 59 patients with CML who entered into the MRC CMLIII Trial by Southern blot hybridization using the (TTAGGG)(4) probe. A...

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Bibliografske podrobnosti
Main Authors: Boultwood, J, Peniket, A, Watkins, F, Shepherd, P, McGale, P, Richards, S, Fidler, C, Littlewood, T, Wainscoat, J
Format: Journal article
Jezik:English
Izdano: 2000