Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions

Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure and accessibility, different and exclusive models have been proposed for the molecular mechanism of...

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Bibliographic Details
Main Authors: Carravilla, P, Chojnacki, J, Rujas, E, Insausti, S, Largo, E, Waithe, D, Apellaniz, B, Sicard, T, Julien, J, Eggeling, C, Nieva, J
Format: Journal article
Language:English
Published: Springer Nature 2019