The increase in thymopoiesis following T cell progenitor therapy is dependent upon the input population and continued interaction between developing T cells and the thymic microenvironment

The inclusion of in vitro derived T cell progenitor (proT) therapy with hematopoietic stem cell transplant (HSCT) aids in the recovery of the thymus damaged by total body irradiation and improves de novo thymopoiesis. To understand the interaction between proTs and the thymic microenvironment, wildt...

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Bibliographic Details
Main Authors: Smith, M, Reichenbach, D, Parker, S, Mohtashami, M, Stefanski, H, Hogquist, K, Holländer, G, Zúñiga-Pflücker, J, Blazar, B
Format: Conference item
Published: American Association of Immunologists 2016