The increase in thymopoiesis following T cell progenitor therapy is dependent upon the input population and continued interaction between developing T cells and the thymic microenvironment
The inclusion of in vitro derived T cell progenitor (proT) therapy with hematopoietic stem cell transplant (HSCT) aids in the recovery of the thymus damaged by total body irradiation and improves de novo thymopoiesis. To understand the interaction between proTs and the thymic microenvironment, wildt...
Main Authors: | Smith, M, Reichenbach, D, Parker, S, Mohtashami, M, Stefanski, H, Hogquist, K, Holländer, G, Zúñiga-Pflücker, J, Blazar, B |
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Format: | Conference item |
Published: |
American Association of Immunologists
2016
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