Solution structure of a hexitol nucleic acid duplex with four consecutive T center dot T base pairs
The structure of the hexitol nucleic acid (HNA) h(GCGCTTTTGCGC) was determined by NMR spectroscopy. This unnatural nucleic acid was developed as a mimic for A-RNA. In solution, the studied sequence is forming a symmetric double-stranded structure with four central consecutive T·T wobble pairs flanke...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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