The allergen Der p3 from house dust mite stimulates store-operated Ca2+ channels and mast cell migration through PAR4 receptors

The house dust mite is the principal source of perennial aeroallergens in man. How these allergens activate innate and adaptive immunity is unclear, and therefore, there are no therapies targeting mite allergens. Here, we show that house dust mite extract activates store-operated Ca2+ channels, a co...

詳細記述

書誌詳細
主要な著者: Lin, Y, Nelson, J, Kramer, H, Parekh, A
フォーマット: Journal article
出版事項: Cell Press 2018