The allergen Der p3 from house dust mite stimulates store-operated Ca2+ channels and mast cell migration through PAR4 receptors

The house dust mite is the principal source of perennial aeroallergens in man. How these allergens activate innate and adaptive immunity is unclear, and therefore, there are no therapies targeting mite allergens. Here, we show that house dust mite extract activates store-operated Ca2+ channels, a co...

全面介紹

書目詳細資料
Main Authors: Lin, Y, Nelson, J, Kramer, H, Parekh, A
格式: Journal article
出版: Cell Press 2018