Functional and inhibition studies on 2-oxoglutarate-dependent oxygenases

Functional and inhibition studies on 2-oxoglutarate-dependent oxygenases

<p>This thesis explores roles of 2-oxoglutarate-dependent (2OG) oxygenases as interfaces that modulate steps in the flow of genetic information in cells in response to oxygen availability. Chapter 1 introduces mechanistic, biochemical and physiological aspects of major subfamilies of 2OG oxyge...

Полное описание

Библиографические подробности
Главный автор:	Thalhammer, A
Другие авторы:	Schofield, C
Формат:	Диссертация
Язык:	English
Опубликовано:	2012
Предметы:	Tumours Oncology Protein chemistry High-Throughput Screening Antibiotics Computer aided molecular and material design Organic synthesis Enzymes Biophysical chemistry DNA damage signalling Biochemistry Organic chemistry

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