Breaking the allergic response by disrupting antibody glycosylation

Allergic reactions arise when people become sensitized to otherwise harmless environmental antigens. In this issue, Shade et al. reveal that the immunoglobulin ε (IgE) antibodies that mediate these reactions have a key vulnerability. They report that the ability of IgE to trigger an allergic reactio...

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Bibliographic Details
Main Author: Crispin, M
Format: Journal article
Published: Rockefeller University Press 2015