The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.

Mutations of the splicing factor-encoding gene U2AF1 are frequent in the myelodysplastic syndromes (MDS), a myeloid malignancy, and other cancers. Patients with MDS suffer from peripheral blood cytopenias, including anemia, and an increasing percentage of bone marrow myeloblasts. We studied the impa...

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Bibliographic Details
Main Authors:	Yip, B, Steeples, V, Repapi, E, Armstrong, R, Llorian, M, Roy, S, Shaw, J, Dolatshad, H, Taylor, S, Verma, A, Bartenstein, M, Vyas, P, Cross, N, Malcovati, L, Cazzola, M, Hellström-Lindberg, E, Ogawa, S, Smith, C, Pellagatti, A, Boultwood, J
Format:	Journal article
Language:	English
Published:	American Society for Clinical Investigation 2017

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.

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