Is lung function associated with bone mineral density? Results from the Hertfordshire Cohort Study

Given limited information available regarding associations between lung function and bone mineral density among healthy subjects, we undertook these analyses in the Hertfordshire Cohort Study. Forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC were not associated with b...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Dennison, E, Dhanwal, D, Shaheen, S, Azagra, R, Reading, I, Jameson, K, Sayer, A, Cooper, C
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2013
Miêu tả
Tóm tắt:Given limited information available regarding associations between lung function and bone mineral density among healthy subjects, we undertook these analyses in the Hertfordshire Cohort Study. Forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC were not associated with bone mineral density at any site; associations with bone mineral content were removed by adjustment for body size. Purpose: There is limited information available regarding the association between lung function and bone mineral density among healthy elderly subjects. We addressed this issue in the Hertfordshire Cohort Study. Methods: From the above cohort, 985 subjects (496 men and 489 women) aged 60-72 years were recruited. All subjects underwent bone density measurements using dual energy X-ray absorptiometry and lung function tests using standardised spirometry. Chronic obstructive pulmonary disease (COPD) was defined as a FEV1/FVC ratio