Probing the cohesin loading reaction using forward genetics and quantitative ChIP-sequencing
<p>Cohesion between sister chromatids that are newly formed in S-phase is crucial to ensure the fidelity of chromosome segregation. The cohesin complex mediates cohesion and is comprised of two SMC proteins, Smc1 and Smc3, with a kleisin subunit, Scc1. The SMCs interact via their hinge domains...
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| Format: | Thesis |
| Language: | English |
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2016
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