Probing the cohesin loading reaction using forward genetics and quantitative ChIP-sequencing

<p>Cohesion between sister chromatids that are newly formed in S-phase is crucial to ensure the fidelity of chromosome segregation. The cohesin complex mediates cohesion and is comprised of two SMC proteins, Smc1 and Smc3, with a kleisin subunit, Scc1. The SMCs interact via their hinge domains...

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書目詳細資料
主要作者: Petela, N
其他作者: Nasmyth, K
格式: Thesis
語言:English
出版: 2016
主題: