Copper-mediated radiosynthesis of [18F]rucaparib
<p>The poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib is used in the clinic to treat <em>BRCA</em>-mutated cancers. Herein, we report two strategies to access the <sup>18</sup>F-isotopologue of rucaparib by applying a copper-mediated nucleophil...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
American Chemical Society
2021
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