Copper-mediated radiosynthesis of [18F]rucaparib

Copper-mediated radiosynthesis of [18F]rucaparib

<p>The poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib is used in the clinic to treat <em>BRCA</em>-mutated cancers. Herein, we report two strategies to access the <sup>18</sup>F-isotopologue of rucaparib by applying a copper-mediated nucleophil...

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Detalhes bibliográficos
Main Authors:	Chen, Z, Destro, G, Guibbal, F, Chan, CY, Cornelissen, B, Gouverneur, V
Formato:	Journal article
Idioma:	English
Publicado em:	American Chemical Society 2021

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