Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59.
The Ly-6 superfamily of cell surface molecules includes CD59, a potent regulator of the complement system that protects host cells from the cytolytic action of the membrane attack complex (MAC). Although its mechanism of action is not well understood, CD59 is thought to prevent assembly of the MAC b...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1997
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