Enantioselective remote functionalisation of cyclic amines by engineered P450BM3 variants
<p>P450 enzymes activate C–H bonds via the insertion of an oxygen atom from atmospheric dioxygen under ambient conditions in water and accept a broad array of endogenous and exogenous organic substrates. P450<sub>BM3</sub> (CYP102A1) has a unique structure, with the electron-transf...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2022
|
| Subjects: |