Human T cells from autoimmune and normal individuals can produce tumor necrosis factor.

T cell clones derived from patients with autoimmune diseases were found to be capable of producing tumor necrosis factor (TNF). This was demonstrated by stimulating the clones, in the absence of accessory cells, with antibodies against the Ti/T3 complex and with recombinant interleukin 2 (IL2). Anal...

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Bibliographic Details
Main Authors: Turner, M, Londei, M, Feldmann, M
Format: Journal article
Language:English
Published: 1987