Growth factor regulation of intracellular pH homeostasis under hypoxic conditions in isolated equine articular chondrocytes.
Hypoxia and acidosis are recognized features of inflammatory arthroses. This study describes the effects of IGF-1 and TGF-β(1) on pH regulatory mechanisms in articular cartilage under hypoxic conditions. Acid efflux, reactive oxygen species (ROS), and mitochondrial membrane potential were measured i...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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