Structure-based analysis of the metal-dependent mechanism of H-N-H endonucleases.

Controversy surrounds the metal-dependent mechanism of H-N-H endonucleases, enzymes involved in a variety of biological functions, including intron homing and DNA repair. To address this issue we determined the crystal structures for complexes of the H-N-H motif containing bacterial toxin colicin E9...

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Bibliographic Details
Main Authors: Maté, M, Kleanthous, K
Format: Journal article
Language:English
Published: 2004