Intensified treatment with high dose rifampicin and levofloxacin compared to standard treatment for adult patients with tuberculous meningitis (TBM-IT): protocol for a randomized controlled trial.

BACKGROUND: Tuberculous meningitis is the most severe form of tuberculosis. Mortality for untreated tuberculous meningitis is 100%. Despite the introduction of antibiotic treatment for tuberculosis the mortality rate for tuberculous meningitis remains high; approximately 25% for HIV-negative and 67...

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Bibliographic Details
Main Authors: Heemskerk, D, Day, J, Chau, T, Dung, N, Yen, N, Bang, N, Merson, L, Olliaro, P, Pouplin, T, Caws, M, Wolbers, M, Farrar, J
Format: Journal article
Language:English
Published: 2011