Radiotherapy-based conditioning is effective immunosuppression for patients undergoing transplantation with T-cell depleted stem cell grafts for severe aplasia.

BACKGROUND: We studied the outcome of individuals with aplastic anemia conditioned with a radiation-containing regimen followed by an infusion of stem cell grafts that had been depleted of lymphocytes with CAMPATH-1H (antiCD52; humanised). METHODS: The conditioning regime consisted of fractionated (...

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Bibliographic Details
Main Authors: Novitzky, N, Thomas, V, Stubbings, H, Hale, G, Waldmann, H
Format: Journal article
Language:English
Published: 2004