Radiotherapy-based conditioning is effective immunosuppression for patients undergoing transplantation with T-cell depleted stem cell grafts for severe aplasia.

BACKGROUND: We studied the outcome of individuals with aplastic anemia conditioned with a radiation-containing regimen followed by an infusion of stem cell grafts that had been depleted of lymphocytes with CAMPATH-1H (antiCD52; humanised). METHODS: The conditioning regime consisted of fractionated (...

Повний опис

Бібліографічні деталі
Автори: Novitzky, N, Thomas, V, Stubbings, H, Hale, G, Waldmann, H
Формат: Journal article
Мова:English
Опубліковано: 2004