Tireless surveillance by exhausted T cells

T cell exhaustion is an evocative concept that results in attenuated function in the face of chronic antigen exposure and is critical to avoid immunopathology. However, tumors often exploit this dampened T cell function to escape the antitumor immune response. In this issue of the JCI, You et al. in...

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Bibliographic Details
Main Author: Dustin, ML
Format: Journal article
Language:English
Published: American Society for Clinical Investigation 2021