Cardiac effects of antimalarial treatment with halofantrine.

In a prospective electrocardiographic study of Karen patients with acute uncomplicated falciparum malaria, mefloquine (25 mg/kg) had no cardiac effects (n = 53), but halofantrine (72 mg/kg) induced consistent dose-related lengthening of the PR and QT intervals in all 61 patients treated. The likelih...

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Détails bibliographiques
Auteurs principaux: Nosten, F, ter Kuile, F, Luxemburger, C, Woodrow, C, Kyle, D, Chongsuphajaisiddhi, T, White, N
Format: Journal article
Langue:English
Publié: 1993