Cardiac effects of antimalarial treatment with halofantrine.

In a prospective electrocardiographic study of Karen patients with acute uncomplicated falciparum malaria, mefloquine (25 mg/kg) had no cardiac effects (n = 53), but halofantrine (72 mg/kg) induced consistent dose-related lengthening of the PR and QT intervals in all 61 patients treated. The likelih...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Nosten, F, ter Kuile, F, Luxemburger, C, Woodrow, C, Kyle, D, Chongsuphajaisiddhi, T, White, N
Format: Journal article
Sprache:English
Veröffentlicht: 1993