Cardiac effects of antimalarial treatment with halofantrine.
In a prospective electrocardiographic study of Karen patients with acute uncomplicated falciparum malaria, mefloquine (25 mg/kg) had no cardiac effects (n = 53), but halofantrine (72 mg/kg) induced consistent dose-related lengthening of the PR and QT intervals in all 61 patients treated. The likelih...
Main Authors: | Nosten, F, ter Kuile, F, Luxemburger, C, Woodrow, C, Kyle, D, Chongsuphajaisiddhi, T, White, N |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1993
|
Similar Items
-
Halofantrine versus mefloquine in treatment of multidrug-resistant falciparum malaria.
by: ter Kuile, F, et al.
Published: (1993) -
Treatment of multidrug-resistant Plasmodium falciparum malaria with 3-day artesunate-mefloquine combination.
by: Nosten, F, et al.
Published: (1994) -
Other 4-methanolquinolines, amyl alcohols and phentathrenes: Mefloquine, lumefantrine and halofantrine
by: Nosten, F, et al.
Published: (2012) -
Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria.
by: Krishna, S, et al.
Published: (1993) -
Comparison of capillary whole blood, venous whole blood, and plasma concentrations of mefloquine, halofantrine, and desbutyl-halofantrine measured by high-performance liquid chromatography.
by: Ter Kuile, F, et al.
Published: (1994)