Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors.

Single cancer stem-like cells (CSC) from colorectal cancers can be functionally identified by their ability to form large lumen-containing colonies in three-dimensional Matrigel cultures. These colonies contain the three types of differentiated colorectal epithelial cells, and single cells obtained...

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Bibliographic Details
Main Authors: Ashley, N, Yeung, T, Bodmer, W
Format: Journal article
Language:English
Published: 2013