Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease

Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease

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Despite recent discoveries in the genetics of sporadic Alzheimer's disease, there remains substantial " hidden heritability." It is thought that some of this missing heritability may be because of gene-gene, i.e., epistatic, interactions. We examined potential epistasis between 110 ca...

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Bibliographic Details
Main Authors: Bullock, J, Medway, C, Cortina-Borja, M, Turton, J, Prince, J, Ibrahim-Verbaas, C, Schuur, M, Breteler, M, van Duijn, C, Kehoe, P, Barber, R, Coto, E, Alvarez, V, Deloukas, P, Hammond, N, Combarros, O, Mateo, I, Warden, DR, Lehmann, MG, Belbin, O, Brown, K, Wilcock, G
Format: Journal article
Published: 2013

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