Reduction in occipital cortex gamma-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects.

BACKGROUND: Studies using proton magnetic resonance spectroscopy (MRS) have indicated that unmedicated, acutely depressed patients have decreased levels of gamma-aminobutyric acid (GABA) in occipital cortex. Cortical levels of glutamate (Glu) may be increased, although these data are less consistent...

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Bibliographic Details
Main Authors: Bhagwagar, Z, Wylezinska, M, Jezzard, P, Evans, J, Ashworth, F, Sule, A, Matthews, P, Cowen, P
Format: Journal article
Language:English
Published: 2007