The antimalarial agent mefloquine inhibits ATP-sensitive K-channels.
The aim of this study was to determine whether antimalarial agents inhibit ATP-sensitive potassium (K(ATP)) channels and thereby contribute to the observed side-effects of these drugs. Mefloquine (10 - 100 microM), but not artenusate (100 microM), stimulated insulin release from pancreatic islets in...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2000
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