Characterisation of alternative H2A.X mRNAs during the cell cycle and under DNA damage conditions
<p>Replication-dependent (RD) histone genes employ a unique RNA processing mechanism that generates non-polyadenylated messenger RNA (mRNA), ending in a stem-loop (SL) structure. This is mediated by a U7 snRNP-dependent mechanism that distinguishes this mRNA class from “bulk” poly(A)+ mRNA. Ho...
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| Format: | Thesis |
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2019
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