Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).

Schistosoma mansoni is the parasite responsible for schistosomiasis, a disease that affects about 218 million people worldwide. Currently, both direct treatment and disease control initiatives rely on chemotherapy using a single drug, praziquantel. Concerns over the possibility of resistance develop...

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Bibliographic Details
Main Authors: Romanello, L, Serrão, V, Torini, JR, Bird, LE, Nettleship, JE, Rada, H, Reddivari, Y, Raymond j., RJ, DeMarco, R, Brandão-Neto, J, Pereira, HD
Format: Journal article
Language:English
Published: Elsevier 2017