Structural dissection and high-throughput screening of mannosylglycerate synthase.

The enzymatic transfer of activated mannose yields mannosides in glycoconjugates and oligo- and polysaccharides. Yet, despite its biological necessity, the mechanism by which glycosyltransferases recognize mannose and catalyze its transfer to acceptor molecules is poorly understood. Here, we report...

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Bibliographic Details
Main Authors: Flint, J, Taylor, E, Yang, M, Bolam, D, Tailford, L, Martinez-Fleites, C, Dodson, E, Davis, B, Gilbert, H, Davies, G
Format: Journal article
Language:English
Published: 2005