Structural dissection and high-throughput screening of mannosylglycerate synthase.
The enzymatic transfer of activated mannose yields mannosides in glycoconjugates and oligo- and polysaccharides. Yet, despite its biological necessity, the mechanism by which glycosyltransferases recognize mannose and catalyze its transfer to acceptor molecules is poorly understood. Here, we report...
Главные авторы: | , , , , , , , , , |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
2005
|